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1.

Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.

Jahangir, Chowdhury Arif; Page, David B; Broeckx, Glenn; Gonzalez, Claudia A; Burke, Caoimbhe; Murphy, Clodagh; Reis-Filho, Jorge S; Ly, Amy; Harms, Paul W; Gupta, Rajarsi R; Vieth, Michael; Hida, Akira I; Kahila, Mohamed; Kos, Zuzana; van Diest, Paul J; Verbandt, Sara; Thagaard, Jeppe; Khiroya, Reena; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Adams, Sylvia; Almeida, Jonas S; Alvarado-Cabrero, Isabel; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Bellolio, Enrique R; Bheemaraju, Vydehi; Blenman, Kim Rm; Botinelly Mendonça Fujimoto, Luciana; Burgues, Octavio; Chardas, Alexandros; Cheang, Maggie Chon U; Ciompi, Francesco; Cooper, Lee Ad; Coosemans, An; Corredor, Germán; Dantas Portela, Flavio Luis; Deman, Frederik; Demaria, Sandra; Dudgeon, Sarah N; Elghazawy, Mahmoud; Fernandez-Martín, Claudio; Fineberg, Susan; Fox, Stephen B; Giltnane, Jennifer M; Gnjatic, Sacha; Gonzalez-Ericsson, Paula I; Grigoriadis, Anita.

J Pathol ; 262(3): 271-288, 2024 03.

Artículo en Inglés | MEDLINE | ID: mdl-38230434

2.

Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

Page, David B; Broeckx, Glenn; Jahangir, Chowdhury Arif; Verbandt, Sara; Gupta, Rajarsi R; Thagaard, Jeppe; Khiroya, Reena; Kos, Zuzana; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Akturk, Guray; Almeida, Jonas S; Alvarado-Cabrero, Isabel; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Bellolio, Enrique R; Bheemaraju, Vydehi; Blenman, Kim Rm; Botinelly Mendonça Fujimoto, Luciana; Bouchmaa, Najat; Burgues, Octavio; Cheang, Maggie Chon U; Ciompi, Francesco; Cooper, Lee Ad; Coosemans, An; Corredor, Germán; Dantas Portela, Flavio Luis; Deman, Frederik; Demaria, Sandra; Dudgeon, Sarah N; Elghazawy, Mahmoud; Ely, Scott; Fernandez-Martín, Claudio; Fineberg, Susan; Fox, Stephen B; Gallagher, William M; Giltnane, Jennifer M; Gnjatic, Sacha; Gonzalez-Ericsson, Paula I; Grigoriadis, Anita; Halama, Niels; Hanna, Matthew G; Harbhajanka, Aparna; Hardas, Alexandros; Hart, Steven N; Hartman, Johan; Hewitt, Stephen; Hida, Akira I.

J Pathol ; 260(5): 514-532, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37608771

3.

Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer

Thagaard, Jeppe; Broeckx, Glenn; Page, David B; Jahangir, Chowdhury Arif; Verbandt, Sara; Kos, Zuzana; Gupta, Rajarsi; Khiroya, Reena; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Akturk, Guray; Almeida, Jonas S; Alvarado-Cabrero, Isabel; Amgad, Mohamed; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Balslev, Eva; Bellolio, Enrique R; Bheemaraju, Vydehi; Blenman, Kim Rm; Botinelly Mendonça Fujimoto, Luciana; Bouchmaa, Najat; Burgues, Octavio; Chardas, Alexandros; Chon U Cheang, Maggie; Ciompi, Francesco; Cooper, Lee Ad; Coosemans, An; Corredor, Germán; Dahl, Anders B; Dantas Portela, Flavio Luis; Deman, Frederik; Demaria, Sandra; Doré Hansen, Johan; Dudgeon, Sarah N; Ebstrup, Thomas; Elghazawy, Mahmoud; Fernandez-Martín, Claudio; Fox, Stephen B; Gallagher, William M; Giltnane, Jennifer M; Gnjatic, Sacha; Gonzalez-Ericsson, Paula I; Grigoriadis, Anita; Halama, Niels; Hanna, Matthew G; Harbhajanka, Aparna; Hart, Steven N.

J Pathol ; 260(5): 498-513, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37608772

4.

Obesity and metabolic syndrome are associated with short-term endocrine therapy resistance in early ER + breast cancer.

Bergman, Riley; Berko, Yvonne A; Sanchez, Violeta; Sanders, Melinda E; Gonzalez-Ericsson, Paula I; Arteaga, Carlos L; Rexer, Brent N.

Breast Cancer Res Treat ; 197(2): 307-317, 2023 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-36396775

5.

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.

Gonzalez-Ericsson, Paula I; Stovgaard, Elisabeth S; Sua, Luz F; Reisenbichler, Emily; Kos, Zuzana; Carter, Jodi M; Michiels, Stefan; Le Quesne, John; Nielsen, Torsten O; Laenkholm, Anne-Vibeke; Fox, Stephen B; Adam, Julien; Bartlett, John Ms; Rimm, David L; Quinn, Cecily; Peeters, Dieter; Dieci, Maria V; Vincent-Salomon, Anne; Cree, Ian; Hida, Akira I; Balko, Justin M; Haynes, Harry R; Frahm, Isabel; Acosta-Haab, Gabriela; Balancin, Marcelo; Bellolio, Enrique; Yang, Wentao; Kirtani, Pawan; Sugie, Tomoharu; Ehinger, Anna; Castaneda, Carlos A; Kok, Marleen; McArthur, Heather; Siziopikou, Kalliopi; Badve, Sunil; Fineberg, Susan; Gown, Allen; Viale, Giuseppe; Schnitt, Stuart J; Pruneri, Giancarlo; Penault-Llorca, Frederique; Hewitt, Stephen; Thompson, E Aubrey; Allison, Kimberly H; Symmans, William F; Bellizzi, Andrew M; Brogi, Edi; Moore, David A; Larsimont, Denis; Dillon, Deborah A.

J Pathol ; 250(5): 667-684, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32129476

6.

WITHDRAWN: Quantitative mass spectrometry analysis of PD-L1 protein expression, N-glycosylation and expression stoichiometry with PD-1 and PD-L2 in human melanoma.

Morales-Betanzos, Carlos A; Lee, Hyoungjoo; Gonzalez-Ericsson, Paula I; Balko, Justin M; Johnson, Douglas B; Zimmerman, Lisa J; Liebler, Daniel C.

Mol Cell Proteomics ; 2017 Apr 17.

Artículo en Inglés | MEDLINE | ID: mdl-28416578

7.

Quantitative Mass Spectrometry Analysis of PD-L1 Protein Expression, N-glycosylation and Expression Stoichiometry with PD-1 and PD-L2 in Human Melanoma.

Morales-Betanzos, Carlos A; Lee, Hyoungjoo; Gonzalez Ericsson, Paula I; Balko, Justin M; Johnson, Douglas B; Zimmerman, Lisa J; Liebler, Daniel C.

Mol Cell Proteomics ; 16(10): 1705-1717, 2017 10.

Artículo en Inglés | MEDLINE | ID: mdl-28546465

8.

Post-irradiation morphoea of the breast: a case report and review of the literature.

Gonzalez-Ericsson, Paula I; Estrada, Monica V; Al-Rohil, Rami; Sanders, Melinda E.

Histopathology ; 72(2): 342-350, 2018 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-29110314

9.

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research.

Hendry, Shona; Salgado, Roberto; Gevaert, Thomas; Russell, Prudence A; John, Tom; Thapa, Bibhusal; Christie, Michael; van de Vijver, Koen; Estrada, M V; Gonzalez-Ericsson, Paula I; Sanders, Melinda; Solomon, Benjamin; Solinas, Cinzia; Van den Eynden, Gert G G M; Allory, Yves; Preusser, Matthias; Hainfellner, Johannes; Pruneri, Giancarlo; Vingiani, Andrea; Demaria, Sandra; Symmans, Fraser; Nuciforo, Paolo; Comerma, Laura; Thompson, E A; Lakhani, Sunil; Kim, Seong-Rim; Schnitt, Stuart; Colpaert, Cecile; Sotiriou, Christos; Scherer, Stefan J; Ignatiadis, Michail; Badve, Sunil; Pierce, Robert H; Viale, Giuseppe; Sirtaine, Nicolas; Penault-Llorca, Frederique; Sugie, Tomohagu; Fineberg, Susan; Paik, Soonmyung; Srinivasan, Ashok; Richardson, Andrea; Wang, Yihong; Chmielik, Ewa; Brock, Jane; Johnson, Douglas B; Balko, Justin; Wienert, Stephan; Bossuyt, Veerle; Michiels, Stefan; Ternes, Nils.

Adv Anat Pathol ; 24(5): 235-251, 2017 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-28777142

10.

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors.

Hendry, Shona; Salgado, Roberto; Gevaert, Thomas; Russell, Prudence A; John, Tom; Thapa, Bibhusal; Christie, Michael; van de Vijver, Koen; Estrada, M V; Gonzalez-Ericsson, Paula I; Sanders, Melinda; Solomon, Benjamin; Solinas, Cinzia; Van den Eynden, Gert G G M; Allory, Yves; Preusser, Matthias; Hainfellner, Johannes; Pruneri, Giancarlo; Vingiani, Andrea; Demaria, Sandra; Symmans, Fraser; Nuciforo, Paolo; Comerma, Laura; Thompson, E A; Lakhani, Sunil; Kim, Seong-Rim; Schnitt, Stuart; Colpaert, Cecile; Sotiriou, Christos; Scherer, Stefan J; Ignatiadis, Michail; Badve, Sunil; Pierce, Robert H; Viale, Giuseppe; Sirtaine, Nicolas; Penault-Llorca, Frederique; Sugie, Tomohagu; Fineberg, Susan; Paik, Soonmyung; Srinivasan, Ashok; Richardson, Andrea; Wang, Yihong; Chmielik, Ewa; Brock, Jane; Johnson, Douglas B; Balko, Justin; Wienert, Stephan; Bossuyt, Veerle; Michiels, Stefan; Ternes, Nils.

Adv Anat Pathol ; 24(6): 311-335, 2017 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-28777143

11.

Endogenous pAKT activity is associated with response to AKT inhibition alone and in combination with immune checkpoint inhibition in murine models of TNBC.

Bullock, Kennady K; Shattuck-Brandt, Rebecca; Scalise, Carly; Luo, Weifeng; Chen, Sheau-Chiann; Saleh, Nabil; Gonzalez-Ericsson, Paula I; Garcia, Guadalupe; Sanders, Melinda E; Ayers, Gregory D; Yan, Chi; Richmond, Ann.

Cancer Lett ; 586: 216681, 2024 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-38311054

12.

Atezolizumab in Combination With Carboplatin and Survival Outcomes in Patients With Metastatic Triple-Negative Breast Cancer: The TBCRC 043 Phase 2 Randomized Clinical Trial.

Lehmann, Brian D; Abramson, Vandana G; Dees, E Claire; Shah, Payal D; Ballinger, Tarah J; Isaacs, Claudine; Santa-Maria, Cesar A; An, Hanbing; Gonzalez-Ericsson, Paula I; Sanders, Melinda E; Newsom, Kimberly C; Abramson, Richard G; Sheng, Quanhu; Hsu, Chih-Yuan; Shyr, Yu; Wolff, Antonio C; Pietenpol, Jennifer A.

JAMA Oncol ; 10(2): 193-201, 2024 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-38095878

13.

NKG2A Is a Therapeutic Vulnerability in Immunotherapy Resistant MHC-I Heterogeneous Triple-Negative Breast Cancer.

Taylor, Brandie C; Sun, Xiaopeng; Gonzalez-Ericsson, Paula I; Sanchez, Violeta; Sanders, Melinda E; Wescott, Elizabeth C; Opalenik, Susan R; Hanna, Ann; Chou, Shu-Ting; Van Kaer, Luc; Gomez, Henry; Isaacs, Claudine; Ballinger, Tarah J; Santa-Maria, Cesar A; Shah, Payal D; Dees, Elizabeth C; Lehmann, Brian D; Abramson, Vandana G; Pietenpol, Jennifer A; Balko, Justin M.

Cancer Discov ; 14(2): 290-307, 2024 Feb 08.

Artículo en Inglés | MEDLINE | ID: mdl-37791898

14.

AXL/WRNIP1 Mediates Replication Stress Response and Promotes Therapy Resistance and Metachronous Metastasis in HER2+ Breast Cancer.

Marquez-Palencia, Mauricio; Reza Herrera, Luis; Parida, Pravat Kumar; Ghosh, Suvranil; Kim, Kangsan; Das, Nikitha M; Gonzalez-Ericsson, Paula I; Sanders, Melinda E; Mobley, Bret C; Diegeler, Sebastian; Aguilera, Todd A; Peng, Yan; Lewis, Cheryl M; Arteaga, Carlos L; Hanker, Ariella B; Whitehurst, Angelique W; Lorens, James B; Brekken, Rolf A; Davis, Anthony J; Malladi, Srinivas.

Cancer Res ; 84(5): 675-687, 2024 03 04.

Artículo en Inglés | MEDLINE | ID: mdl-38190717

15.

Polycomb repressor complex 2 suppresses interferon-responsive MHC-II expression in melanoma cells and is associated with anti-PD-1 resistance.

James, Jamaal L; Taylor, Brandie C; Axelrod, Margaret L; Sun, Xiaopeng; Guerin, Lindsey N; Gonzalez-Ericsson, Paula I; Wang, Yu; Sanchez, Violeta; Fahey, Catherine C; Sanders, Melinda E; Xu, Yaomin; Hodges, Emily; Johnson, Douglas B; Balko, Justin M.

J Immunother Cancer ; 11(11)2023 11 20.

Artículo en Inglés | MEDLINE | ID: mdl-38315170

16.

Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases.

Parida, Pravat Kumar; Marquez-Palencia, Mauricio; Ghosh, Suvranil; Khandelwal, Nitin; Kim, Kangsan; Nair, Vidhya; Liu, Xiao-Zheng; Vu, Hieu S; Zacharias, Lauren G; Gonzalez-Ericsson, Paula I; Sanders, Melinda E; Mobley, Bret C; McDonald, Jeffrey G; Lemoff, Andrew; Peng, Yan; Lewis, Cheryl; Vale, Gonçalo; Halberg, Nils; Arteaga, Carlos L; Hanker, Ariella B; DeBerardinis, Ralph J; Malladi, Srinivas.

Nat Cancer ; 4(6): 893-907, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-37248394

17.

FGFR1 Antibody Validation and Characterization of FGFR1 Protein Expression in ER+ Breast Cancer.

Gonzalez-Ericsson, Paula I; Servetto, Alberto; Formisano, Luigi; Sánchez, Violeta; Mayer, Ingrid A; Arteaga, Carlos L; Sanders, Melinda E.

Appl Immunohistochem Mol Morphol ; 30(9): 600-608, 2022 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-36083147

18.

Peripheral Blood Monocyte Abundance Predicts Outcomes in Patients with Breast Cancer.

Axelrod, Margaret L; Wang, Yu; Xu, Yaomin; Sun, Xiaopeng; Bejan, Cosmin A; Gonzalez-Ericsson, Paula I; Nunnery, Sara; Bergman, Riley E; Donaldson, Joshua; Guerrero-Zotano, Angel L; Massa, Chiara; Seliger, Barbara; Sanders, Melinda; Mayer, Ingrid A; Balko, Justin M.

Cancer Res Commun ; 2(5): 286-292, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-36304942

19.

Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness.

Parida, Pravat Kumar; Marquez-Palencia, Mauricio; Nair, Vidhya; Kaushik, Akash K; Kim, Kangsan; Sudderth, Jessica; Quesada-Diaz, Eduardo; Cajigas, Ambar; Vemireddy, Vamsidhara; Gonzalez-Ericsson, Paula I; Sanders, Melinda E; Mobley, Bret C; Huffman, Kenneth; Sahoo, Sunati; Alluri, Prasanna; Lewis, Cheryl; Peng, Yan; Bachoo, Robert M; Arteaga, Carlos L; Hanker, Ariella B; DeBerardinis, Ralph J; Malladi, Srinivas.

Cell Metab ; 34(1): 90-105.e7, 2022 01 04.

Artículo en Inglés | MEDLINE | ID: mdl-34986341

20.

Epigenetic Repression of STING by MYC Promotes Immune Evasion and Resistance to Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer.

Lee, Kyung-Min; Lin, Chang-Ching; Servetto, Alberto; Bae, Joonbeom; Kandagatla, Vishal; Ye, Dan; Kim, GunMin; Sudhan, Dhivya R; Mendiratta, Saurabh; González Ericsson, Paula I; Balko, Justin M; Lee, Jeon; Barnes, Spencer; Malladi, Venkat S; Tabrizi, Siamak; Reddy, Sangeetha M; Yum, Seoyun; Chang, Ching-Wei; Hutchinson, Katherine E; Yost, Susan E; Yuan, Yuan; Chen, Zhijian J; Fu, Yang-Xin; Hanker, Ariella B; Arteaga, Carlos L.

Cancer Immunol Res ; 10(7): 829-843, 2022 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-35561311

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